Articles by author - Jana Navarová

Glucomannan in prevention of oxidative stress and inflammation occurring in adjuvant arthritis.

Bauerova K, Ponist S, Navarova J, Dubnickova M, Paulovicova E, Pajtinka M, Kogan G, Mihalova D.

Journal Article 2008; 29(5): 691-696 PubMed PMID: 18987599  Keywords:  Animals, Anti-Inflammatory Agents, Non-Steroidal, Antioxidants:metabolism, Arthritis, Experimental:pathology, Candida:chemistry, Foot:pathology, Inflammation:pathology, Male, Mannans:pharmacology, Mycobacterium:immunology, Oxidative Stress:drug effects, P.    Citation

OBJECTIVES: The aim of this study was to evaluate the effects of a biological response modifier, glucomannan (GM), isolated from Candida u.....

Read abstract  Full text PDF

Prenatal developmental toxicity study of the pyridoindole antioxidant SMe1EC2 in rats.

Ujhazy E, Dubovicky M, Ponechalova V, Navarova J, Brucknerova I, Snirc V, Mach M.

Journal Article 2008; 29(5): 639-643 PubMed PMID: 18987587  Keywords:  Abnormalities, Drug-Induced:pathology, Animals, Antioxidants:toxicity, Female, Fetal Development:drug effects, Fetal Diseases:chemically induced, Indoles:toxicity, Neuroprotective Agents:toxicity, Pregnancy, Pyridines:toxicity, Rats, Rats, Wistar, Reprodu.    Citation

OBJECTIVE: The 2-ethoxycarbonyl-8-methoxy-2,3,4,4a,5,9b-hexahydro-1H-pyrido-[4,3b] indolinium chloride (SMe1EC2) is a prospective antioxid.....

Read abstract  Full text PDF

Cardiovascular toxicity of the first line cancer chemotherapeutic agents: doxorubicin, cyclophosphamide, streptozotocin and bevacizumab.

Drímal J, Zúrová-Nedelcevová J, Knezl V, Sotníková R, Navarová J.

Evaluation Studies 2006; 27(Suppl 2): 176-179 PubMed PMID: 17159809  Keywords:  Animals, Antibodies, Monoclonal:adverse effects, Antibodies, Monoclonal, Humanized, Antineoplastic Agents:adverse effects, Bevacizumab, Cardiomyopathies:chemically induced, Chemokine CCL2:metabolism, Cyclophosphamide:adverse effects, Doxorubicin:adverse e.    Citation

OBJECTIVES: Although the mechanisms responsible for the occurrence of congestive heart failure after anti-cancer therapy are largely unkno.....

Read abstract

Participation of reactive oxygen species in diabetes-induced endothelial dysfunction.

Zúrová-Nedelcevová J, Navarová J, Drábiková K, Jancinová V, Petríková M, Bernátová I, Kristová V, Snirc V, Nosál'ová V, Sotníková R.

Journal Article 2006; 27(Suppl 2): 168-171 PubMed PMID: 17159807  Keywords:  Acetylcholine:pharmacology, Animals, Diabetes Mellitus, Experimental:complications, Diabetic Angiopathies:etiology, Hyperglycemia:complications, Male, Phenylephrine:pharmacology, Rats, Rats, Wistar, Reactive Oxygen Species:adverse effects, Streptozocin, V.    Citation

OBJECTIVES: In the present study, the relationship between diabetes-induced hyperglycemia, reactive oxygen species production and endothel.....

Read abstract

Effect of acetylcholine and ischaemia/reperfusion injury on the heart of rats with STZ-induced experimental diabetes.

Knezl V, Kysel'ová Z, Zúrová-Nedelcevová J, Navarová J, Tribulová N, Drímal J.

Comparative Study 2006; 27(Suppl 2): 144-147 PubMed PMID: 17159801  Keywords:  Acetylcholine:pharmacology, Animals, Diabetes Mellitus, Experimental:complications, Diabetic Angiopathies:complications, Evoked Potentials:drug effects, Heart:drug effects, Male, Myocardial Ischemia:complications, Rats, Rats, Wistar, Reperfusion Injury:co.    Citation

OBJECTIVES: To investigate the effect of acetylcholine (ACh) and ischaemia/reperfusion injury on functional changes and dysrhythmias of th.....

Read abstract