Altered dopamine D1 and D2 receptor mRNA expression in mesencephalon from mice exposed to repeated treatments with methamphetamine and cannabinoid CB1 agonist methanandamide.

Landa L, Jurajda M, Sulcova A.

Journal Article 2012; 33(4): 446-452 PubMed PMID: 22936253 Keywords: Animals, Arachidonic Acids:pharmacology, Behavior, Animal:drug effects, Central Nervous System Sensitization:drug effects, Dopamine Agents:pharmacology, Drug Administration Schedule, Drug Interactions, Male, Mesencephalon:drug effects, Methamphetamine:pha.

OBJECTIVES: In our previous studies we found that both acute administration of CB1 receptor agonist methanandamide and repeated methanandamide pre-treatment prior to methamphetamine challenge dose elicited increase in the CB1 receptor mRNA expression in the mouse mesencephalon. As a reciprocal cross-talk is reported between the cannabin.....

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Vol. 33 (4) 2012 Neuro endocrinology letters

Altered dopamine D1 and D2 receptor mRNA expression in mesencephalon from mice exposed to repeated treatments with methamphetamine and cannabinoid CB1 agonist methanandamide.

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