Vol. 28 (6) 2007 Neuro endocrinology letters

The role of some new factors in the pathophysiology of depression and cardiovascular disease: overview of recent research.

: Depressive disorders and cardiovascular disease are inter-connected by a whole range of pathophysiological mechanisms. Three biological mechanisms are fundamental: activation of the hypothalamus-hypohysis-adrenal axis with a subsequent increase in sympathetic-adrenal system activity, decrease in vagal tone with a decrease in heart rat.....