Vol. 27 (Suppl 2) 2006 Neuro endocrinology letters

Content of protein carbonyl groups in gerbil brain after reversible bilateral carotid occlusion: effect of 2,3-dihydromelatonin.

OBJECTIVES: To investigate whether a new derivative of melatonin, (2,3-dihydromelatonin (DHM), prevented the oxidative stress induced by ischemia /reperfusion (I/R) in the gerbil brain. To specify the effect on endogenous antioxidant activity and protein modification in the brain cortex, we evaluated the contents of glutathione (total G.....